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p63 Antikörper

TP63 Reaktivität: Human IHC, IF, FACS Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6297602
  • Target Alle p63 (TP63) Antikörper anzeigen
    p63 (TP63) (Tumor Protein P63 (TP63))
    Reaktivität
    • 59
    • 22
    • 20
    • 4
    • 2
    • 2
    Human
    Wirt
    • 44
    • 19
    • 1
    Kaninchen
    Klonalität
    • 38
    • 26
    Polyklonal
    Konjugat
    • 54
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser p63 Antikörper ist unkonjugiert
    Applikation
    • 37
    • 25
    • 22
    • 12
    • 10
    • 9
    • 8
    • 8
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
    Verwendungszweck
    Rabbit anti-Human p63 Antibody / Tumor protein 63 [Sodium Azide Free]
    Spezifität
    Nuclear
    Aufreinigung
    Recombinant partial human p53 protein was used as the immunogen for this p63 antibody.
    Immunogen
    Recombinant partial human p53 protein was used as the immunogen for this p63 antibody.
    Top Product
    Discover our top product TP63 Primärantikörper
  • Applikationshinweise
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 1-2 μg/mL
    Immunohistochemistry (FFPE): 1-2 μg/mL for 30 minutes at RT
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    In 1X PBS, BSA free, sodium azide free
    Konservierungsmittel
    Azide free
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • Target
    p63 (TP63) (Tumor Protein P63 (TP63))
    Andere Bezeichnung
    Tumor protein 63 (TP63 Produkte)
    Hintergrund

    Target Description: p63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands, however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90 % . Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80 %. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.

    Gene Symbol: TP63///KET///P63///P73H///P73L///TP73L

    Gen-ID
    8626
    UniProt
    Q9H3D4
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