p63 Antikörper
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- Target Alle p63 (TP63) Antikörper anzeigen
- p63 (TP63) (Tumor Protein P63 (TP63))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser p63 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- Verwendungszweck
- Rabbit anti-Human p63 Antibody / Tumor protein 63 [Sodium Azide Free]
- Spezifität
- Nuclear
- Aufreinigung
- Recombinant partial human p53 protein was used as the immunogen for this p63 antibody.
- Immunogen
- Recombinant partial human p53 protein was used as the immunogen for this p63 antibody.
- Top Product
- Discover our top product TP63 Primärantikörper
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- Applikationshinweise
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Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 minutes at RT - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- In 1X PBS, BSA free, sodium azide free
- Konservierungsmittel
- Azide free
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Target
- p63 (TP63) (Tumor Protein P63 (TP63))
- Andere Bezeichnung
- Tumor protein 63 (TP63 Produkte)
- Hintergrund
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Target Description: p63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands, however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90 % . Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80 %. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.
Gene Symbol: TP63///KET///P63///P73H///P73L///TP73L
- Gen-ID
- 8626
- UniProt
- Q9H3D4
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