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TSH receptor Antikörper

TSHR Reaktivität: Human IHC, FACS, IF Wirt: Maus Monoclonal unconjugated
Produktnummer ABIN6297580
  • Target Alle TSH receptor (TSHR) Antikörper anzeigen
    TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
    Reaktivität
    • 79
    • 54
    • 35
    • 9
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    Human
    Wirt
    • 67
    • 15
    • 1
    • 1
    Maus
    Klonalität
    • 68
    • 16
    Monoklonal
    Konjugat
    • 45
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TSH receptor Antikörper ist unkonjugiert
    Applikation
    • 45
    • 42
    • 20
    • 15
    • 14
    • 13
    • 13
    • 9
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
    Verwendungszweck
    Mouse anti-Human Thyroid Stimulating Hormone Receptor / TSHR Antibody (alpha chain) [Sodium Azide Free]
    Spezifität
    Cytoplasmic, cell surface
    Aufreinigung
    Recombinant human TSH Receptor alpha chain protein was used as the immunogen for this TSHR antibody.
    Immunogen
    Recombinant human TSH Receptor alpha chain protein was used as the immunogen for this TSHR antibody.
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    Discover our top product TSHR Primärantikörper
  • Applikationshinweise
    FACS: 0.5-1 μg/10^6 cells in 0.1ml
    IF: 1-2 μg/mL
    IHC (FFPE): 0.5-1 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    In 1X PBS, BSA free, sodium azide free
    Konservierungsmittel
    Azide free
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • Target
    TSH receptor (TSHR) (Thyroid Stimulating Hormone Receptor (TSHR))
    Andere Bezeichnung
    Thyrotropin receptor (TSHR Produkte)
    Synonyme
    CHNG1 antikoerper, LGR3 antikoerper, hTSHR-I antikoerper, AI481368 antikoerper, hypothroid antikoerper, hyt antikoerper, pet antikoerper, TSHRA antikoerper, TSH-R antikoerper, thyroid stimulating hormone receptor antikoerper, tshr antikoerper, TSHR antikoerper, Tshr antikoerper
    Hintergrund

    Target Description: Thyroid-stimulating hormone (TSH, also known as thyrotropin) is a glycoprotein involved in the control of thyroid structure and metabolism, which stimulates the release of the thyroid hormones. TSH is regulated by thyroid hormone (T3) and various retinoid compounds. TSH binds to the thyroid-stimulating hormone receptor (TSHR), which is cleaved into two subunits, A and B, and plays a major role in regulating thyroid function. The third cytoplasmic loop of TSHR has been identified as critical for its role in regulating inositol phosphate and cAMP formation. In Graves disease, an autoimmune disorder, TSHR is activated by autoantibodies, which may be stimulated by the cleavage of the A and B subunits.

    Gene Symbol: TSHR///LGR3

    Gen-ID
    7253
    UniProt
    P16473
    Pathways
    Thyroid Hormone Synthesis
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