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ANO1 Antikörper

ANO1 Reaktivität: Human IHC Wirt: Maus Monoclonal unconjugated
Produktnummer ABIN6297578
  • Target Alle ANO1 Antikörper anzeigen
    ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))
    Reaktivität
    • 128
    • 31
    • 29
    • 7
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    Human
    Wirt
    • 82
    • 50
    Maus
    Klonalität
    • 68
    • 64
    Monoklonal
    Konjugat
    • 58
    • 13
    • 9
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ANO1 Antikörper ist unkonjugiert
    Applikation
    • 63
    • 52
    • 43
    • 37
    • 35
    • 20
    • 18
    • 13
    • 13
    • 9
    • 4
    • 3
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC)
    Verwendungszweck
    Mouse anti-Human TMEM16A Antibody (DOG1) [IHC only]
    Spezifität
    Cell Surface and Cytoplasmic
    Aufreinigung
    Recombinant human TMEM16A/DOG1 protein was used as the immunogen for this TMEM16A antibody.
    Immunogen
    Recombinant human TMEM16A/DOG1 protein was used as the immunogen for this TMEM16A antibody.
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  • Applikationshinweise
    Prediluted format : incubate for 30 min at RT (2)
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • Target
    ANO1 (Anoctamin 1, Calcium Activated Chloride Channel (ANO1))
    Andere Bezeichnung
    Anoctamin-1 (ANO1 Produkte)
    Synonyme
    DOG1 antikoerper, ORAOV2 antikoerper, TAOS2 antikoerper, TMEM16A antikoerper, Tmem16a antikoerper, anoctamin 1 antikoerper, anoctamin 1, calcium activated chloride channel antikoerper, Ano1 antikoerper, ANO1 antikoerper
    Hintergrund

    Target Description: Expression of TMEM16A (DOG1) protein is elevated in the gastrointestinal stromal tumors (GIST 's), c-kit signaling-driven mesenchymal tumors of the GI tract. It is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for TMEM16A has been reported in 97.8 percent of scorable GIST 's, including all c-kit negative GIST 's. Overexpression has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha (PDGFR alpha) mutants that fail to express c-kit antigen. The overall sensitivity of TMEM16A and c-kit in GIST 's is nearly identical: 94.4 % vs. 94.7 %.

    Gene Symbol: ANO1///DOG1///ORAOV2///TAOS2///TMEM16A

    Gen-ID
    55107
    UniProt
    Q5XXA6
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