TYMS Antikörper
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- Target Alle TYMS Antikörper anzeigen
- TYMS (Thymidylate Synthetase (TYMS))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser TYMS Antikörper ist unkonjugiert
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Applikation
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (IHC)
- Verwendungszweck
- Mouse anti-Human Thymidylate Synthase Antibody [Sodium Azide Free]
- Spezifität
- Cytoplasmic
- Aufreinigung
- Recombinant human Thymidylate synthase was used as the immunogen for this antibody.
- Immunogen
- Recombinant human Thymidylate synthase was used as the immunogen for this antibody.
- Top Product
- Discover our top product TYMS Primärantikörper
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anti-Thymidylate Synthetase (TYMS) (AA 36-313) antibody
TYMS Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Thymidylate Synthetase (TYMS) (AA 111-210) antibodyTYMS Reaktivität: Human WB, IF, ELISA, IHC (p) Wirt: Maus Monoclonal 3A1 unconjugated
anti-Thymidylate Synthetase (TYMS) (AA 60-174) antibodyTYMS Reaktivität: Human WB, IF, FACS, IHC, ISt, RIA, StM Wirt: Maus Monoclonal TYMS-1884 unconjugated
anti-Thymidylate Synthetase (TYMS) antibodyTYMS Reaktivität: Human WB, IF, IHC (p), IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Thymidylate Synthetase (TYMS) antibodyTYMS Reaktivität: Human WB, IHC, IHC (p) Wirt: Maus Monoclonal 1D6 unconjugated
anti-Thymidylate Synthetase (TYMS) (AA 265-294), (C-Term) antibodyTYMS Reaktivität: Human WB, IF, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB20041 unconjugated
anti-Thymidylate Synthetase (TYMS) antibodyTYMS Reaktivität: Human WB, IHC, IHC (p) Wirt: Maus Monoclonal 5H8 unconjugated
anti-Thymidylate Synthetase (TYMS) (AA 111-210) antibodyTYMS Reaktivität: Human WB, ELISA, IHC (p), IP Wirt: Maus Monoclonal 2B2 unconjugated
anti-Thymidylate Synthetase (TYMS) (AA 2-54) antibodyTYMS Reaktivität: Human WB, IF, ELISA, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Thymidylate Synthetase (TYMS) antibodyTYMS Reaktivität: Human, Maus, Ratte IF Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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FACS: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2) - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
- Konservierungsmittel
- Azide free
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Target
- TYMS (Thymidylate Synthetase (TYMS))
- Andere Bezeichnung
- Thymidylate synthase (TYMS Produkte)
- Substanzklasse
- Viral Protein
- Hintergrund
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Target Description: This antibody is specific for a protein of 36 kDa, identified as Thymidylate Synthase (TS). Thymidylate synthase converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. Thymidylate synthase is also a critical target for the fluoropyrimidines, an important group of anti-neoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates thymidylate synthase by formation of a ternary covalent complex in the presence of the folate cofactor 5,10-methylenetetrahydrofolate. Expression of thymidylate synthase protein is associated with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas.
Gene Symbol: TYMS///TS///OK///SW-cl.29
- Gen-ID
- 7298
- UniProt
- P04818
- Pathways
- Mitotic G1-G1/S Phases
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