MLANA Antikörper

Produktnummer ABIN6297246

Dieses Anti-MLANA-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von MLANA in WB, IF, FACS und IHC. Geeignet für Human, Maus, Ratte und Hund.

Kurzübersicht für MLANA Antikörper (ABIN6297246)

Target: MLANA (Melan A (MLANA))

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MLANA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (IHC)

Produktdetails anti-MLANA Antikörper

Verwendungszweck: Mouse anti-Human/Mouse/Rat/Dog Melan-A Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic

Aufreinigung: Recombinant human MLANA protein was used as the immunogen for the Melan-A antibody.

Immunogen: Recombinant human MLANA protein was used as the immunogen for the Melan-A antibody.

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
Western blot: 0.5-1 μg/mL
Prediluted format: incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu MLANA

Target: MLANA (Melan A (MLANA))

Andere Bezeichnung: Melanoma antigen recognized by T-cells 1

Hintergrund:

Target Description: This antibody recognizes a protein doublet of 20-22 kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This mAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.

Gene Symbol: MLANA///MART1

Gen-ID: 2315

UniProt: Q16655