Desmin Antikörper

Produktnummer ABIN6297155

Der Maus-Monoklonal Anti-Desmin-Antikörper wurde für WB, IHC, IF und FACS validiert. Er ist geeignet zum Nachweis von Desmin in Proben aus Human, Ratte, Maus, Huhn und Hamster. }

Kurzübersicht für Desmin Antikörper (ABIN6297155)

Target: Desmin (DES)

Reaktivität: Human, Ratte, Maus, Huhn, Hamster

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Desmin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-Desmin Antikörper

Verwendungszweck: Mouse anti-Human/Mouse/Rat/Hamster/Chicken Desmin Antibody (Muscle cell marker) [Sodium Azide Free]

Spezifität: Cytoplasmic

Aufreinigung: Recombinant human Desmin was used as the immunogen for the Desmin antibody.

Immunogen: Recombinant human Desmin was used as the immunogen for the Desmin antibody.

Anwendungsinformationen

Applikationshinweise: WB: 0.5-1 μg/mL
FACS: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu Desmin

Target: Desmin (DES)

Andere Bezeichnung: Desmin

Hintergrund:

Target Description: Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain alpha-helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin.

Gene Symbol: DES

Gen-ID: 1674

UniProt: P17661