P24 Capsid Protein Antikörper

Produktnummer ABIN6297130

Dieser Maus Monoklonal Antikörper detektiert spezifisch P24 Capsid Protein in Coat, ELISA, ICC und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für P24 Capsid Protein Antikörper (ABIN6297130)

Target: P24 Capsid Protein

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Applikation: Coating (Coat), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktdetails

Verwendungszweck: Mouse anti-Human HIV Type-1 p24 Antibody [Sodium Azide Free]

Spezifität: Membrane

Aufreinigung: Recombinant HIV-1 Gag p24 protein was used as the immunogen for this antibody.

Immunogen: Recombinant HIV-1 Gag p24 protein was used as the immunogen for this antibody.

Anwendungsinformationen

Applikationshinweise: ELISA: order BSA-free format for coating
Immunocytochemistry (Acetone or paraformaldehyde fixed): 0.5-1 μg/mL for 30 min
IF: 0.5-1 μg/mL,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Antigendetails

Target: P24 Capsid Protein

Andere Bezeichnung: Capsid protein p24 ]

Substanzklasse: Viral Protein

Hintergrund:

Target Description: Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins, which are required for virus particle assembly. HIV-1 Gag p24 is a capsid protein that constitutes the core of AIDS virus HIV-1. p6 and p7 are the components of the nucleocapsid, and p17 provides a protective matrix. HIV-1 Gag p24 is indispensable to the reproduction of AIDS virus and constitutes an essential element for the AIDS virus particle construction. As this protein is detectable from the early stage of AIDS virus infection, its measurement is commonly used as an indicator of HIV-1 infection and viral load.

Gene Symbol: gag-pol

Gen-ID: 155348

UniProt: P04585