CDR2 Antikörper (N-Term)
Kurzübersicht für CDR2 Antikörper (N-Term) (ABIN629700)
Target
Alle CDR2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Spezifität
- CDR2 antibody was raised against the N terminal of CDR2
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Aufreinigung
- Purified
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Immunogen
- CDR2 antibody was raised using the N terminal of CDR2 corresponding to a region with amino acids MLAENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQ
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Applikationshinweise
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WB: 5 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator. -
Kommentare
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CDR2 Blocking Peptide, (ABIN5612802), is also available for use as a blocking control in assays to test for specificity of this CDR2 antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of CDR2 antibody in PBS
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Konzentration
- Lot specific
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Buffer
- PBS
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Handhabung
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- CDR2 (Cerebellar Degeneration-Related Protein 2, 62kDa (CDR2))
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Andere Bezeichnung
- CDR2
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Hintergrund
- Cdr2 normally sequesters c-Myc in the neuronal cytoplasm, thereby down-regulating c-Myc activity, and suggest a mechanism whereby inhibition of cdr2 function by autoantibodies in PCD may contribute to Purkinje neuronal.
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Molekulargewicht
- 52 kDa (MW of target protein)
Target
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