JUP Antikörper

Produktnummer ABIN6296917

Dieses Maus Monoklonal-Antikörper erkennt spezifisch JUP in WB, IF und IP. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Huhn, Rind (Kuh), Hund und Cat.

Kurzübersicht für JUP Antikörper (ABIN6296917)

Target: JUP (Junction Plakoglobin (JUP))

Reaktivität: Human, Maus, Ratte, Huhn, Rind (Kuh), Hund, Cat

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser JUP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Produktdetails anti-JUP Antikörper

Verwendungszweck: Mouse anti-Human/Mouse/Rat/Cat/Dog/Chicken/Cow Gamma Catenin Antibody / Plakoglobin [Sodium Azide Free]

Spezifität: Cell surface, cytoplasmic, cell junctions

Aufreinigung: Recombinant full length chicken gamma Catenin was used as the immunogen for the Plakoglobin antibody.

Immunogen: Recombinant full length chicken gamma Catenin was used as the immunogen for the Plakoglobin antibody.

Anwendungsinformationen

Applikationshinweise: Immunofluorescence: 1-2 μg/mL
WB: 0.5-1 μg/mL
Immunoprecipitation: suitable

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu JUP

Target: JUP (Junction Plakoglobin (JUP))

Andere Bezeichnung: Junction plakoglobin

Hintergrund:

Target Description: Plakoglobin, or gamma Catenin, is a common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of Plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity). [UniProt]

Gene Symbol: JUP///CTNNG///DP3

Gen-ID: 3728

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location