Myeloid Cell Marker Antikörper

Produktnummer ABIN6296505

Der Maus Monoklonal anti-Myeloid Cell Marker Antikörper (ABIN6296505) detektiert spezifisch Myeloid Cell Marker in FACS, IF und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Myeloid Cell Marker Antikörper (ABIN6296505)

Target: Myeloid Cell Marker

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)

Produktdetails

Verwendungszweck: Mouse anti-Human Myeloid Cell Marker Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic and nuclear

Aufreinigung: Human peripheral blood mononuclear cells were used as the immunogen for this Myeloid cell marker antibody.

Immunogen: Human peripheral blood mononuclear cells were used as the immunogen for this Myeloid cell marker antibody.

Anwendungsinformationen

Applikationshinweise: FACS: 0.5-1 μg/million cells
IF: 1-2 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Antigendetails

Target: Myeloid Cell Marker

Hintergrund:

Target Description: This antibody recognizes a 183 kDa protein with DNA-binding characteristics, which is identified as a myeloid cell specific antigen. Clone BM-1 antibody reacts with myeloid precursor cells and granulocytes in bone marrow. Its antigen appears to be restricted to M2 and M3 acute myelogenous leukemia (AML) subtypes. This type of marker is useful in the identification of different levels of cellular differentiation. BM-1 and BM-2 antibodies react with early precursor and mature forms of human myeloid cells. This mAb is useful in the identification of myelogenous leukemias, distinguishing granulocytic sarcomas from lymphoid malignancies and also in the study of differentiation and transformation of human myeloid cells. The biological function of the marker protein is not clear, although it has been proposed that it may play a role in cell differentiation.