Cytokeratin 1 Antikörper (PE)

Produktnummer ABIN6296411

Der Maus Monoklonal Anti-Cytokeratin 1-Antikörper wurde für FACS, IF und T validiert. Er ist geeignet, Cytokeratin 1 in Proben von Human, Ratte, Maus, Rind (Kuh), Kaninchen, Huhn, Affe und Hund zu detektieren.

Kurzübersicht für Cytokeratin 1 Antikörper (PE) (ABIN6296411)

Target: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Kaninchen, Huhn, Affe, Hund

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Cytokeratin 1 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Test (T)

Produktdetails anti-Cytokeratin 1 Antikörper (PE)

Verwendungszweck: Mouse anti-Human/Monkey/Cow/Dog/Rabbit/Mouse/Rat/Chicken Pan Cytokeratin Antibody Cocktail [PE Conjugated]

Spezifität: Cytoplasmic

Aufreinigung: Human epidermal keratin was used as the immunogen for this pan Cytokeratin antibody.

Immunogen: Human epidermal keratin was used as the immunogen for this pan Cytokeratin antibody.

Anwendungsinformationen

Applikationshinweise: Flow Cytometry : 5 µL/test/million cells or 5 µL/test/100 µL of whole blood
Immunofluorescence: 1:50-1:100 for 30 minutes at RT (1)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: 2-8°C. The conjugate is light-sensitive, protect from light.

Details zu Cytokeratin 1

Target: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Andere Bezeichnung: Keratin, type II cytoskeletal 1

Hintergrund:

Target Description: Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI <5.7) and basic (pI >6.0) subfamilies. This pan keratin antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which include CK1, CK3-6, CK8, CK10, CK14-16, and CK19. Many studies have shown the usefulness of cytokeratin markers in cancer research and tumor diagnosis. The AE1 + AE3 antibody cocktail is a broad spectrum pan cytokeratin antibody cocktail which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. It stains cytokeratin present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas.

Gene Symbol: KRT1///KRTA///KRT3///KRT3///KRT5///KRT6A///K6A///KRT6D///KRT8///CYK8///KRT10///KPP///KRT14///KRT15///KRTB///KRT16///KRT16A

UniProt: P04264, P12035, P13647, P02538, P05787, P13645, P02533, P19012, P08779, P08727