CNN1 Antikörper

Produktnummer ABIN6296236

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CNN1 in FACS, IF und IHC. Er zeigt eine Reaktivität gegenüber Human und Ratte.

Kurzübersicht für CNN1 Antikörper (ABIN6296236)

Target: CNN1 (Calponin 1 (CNN1))

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CNN1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)

Produktdetails anti-CNN1 Antikörper

Verwendungszweck: Mouse anti-Human/Rat Calponin Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic

Aufreinigung: Crude human uterus extract was used as the immunogen for the Calponin antibody.

Immunogen: Crude human uterus extract was used as the immunogen for the Calponin antibody.

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu CNN1

Target: CNN1 (Calponin 1 (CNN1))

Andere Bezeichnung: Calponin-1

Hintergrund:

Target Description: Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist, a 34 kDa form and a 29 kDa form. Expression of the 29 kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this mAb reacts with only the 34 kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.

Gene Symbol: CNN1

Gen-ID: 1264

UniProt: P51911