Fibronectin Antikörper

Produktnummer ABIN6296126

Der Maus Monoklonal Anti-Fibronectin-Antikörper wurde für IHC, IF und FACS validiert. Er ist geeignet, Fibronectin in Proben von Human, Ratte, Maus und Schwein zu detektieren.

Kurzübersicht für Fibronectin Antikörper (ABIN6296126)

Target: Fibronectin

Reaktivität: Human, Ratte, Maus, Schwein

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Fibronectin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-Fibronectin Antikörper

Verwendungszweck: Mouse anti-Human/Pig/Mouse/Rat Fibronectin Antibody [Sodium Azide Free]

Spezifität: Connective tissue matrix

Aufreinigung: A T-cell lymphoma biopsy was used as the immunogen for this fibronectin antibody.

Immunogen: A T-cell lymphoma biopsy was used as the immunogen for this fibronectin antibody.

Anwendungsinformationen

Applikationshinweise: FACS: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu Fibronectin

Target: Fibronectin

Hintergrund:

Target Description: Fibronectin is a soluble dimeric glycoprotein of 440 kDa, which is present in cells, extracellular matrix, and blood. There are two types of fibronectin: soluble fibronectin which is produced by hepatocytes and found in blood plasma, and insoluble cellular fibronectin which is produced by fibroblasts in a soluble form and latter assembled into an insoluble form via fibril formation.This antibody reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this antibody localizes to tumor vessels where it binds to the underlying basement. The Fibronectin epitope recognized by this antibody is not accessible in normal tissues to the circulating antibody indicating that it can be used to specifically target tumor vessels in vivo. Clone TV-1 fibronectin antibody is reportedly useful for delivering vasoactive agents to tumors to induce increased vascular permeability or blood flow prior to treatment with chemotherapeutic drugs or antibodies.

Gene Symbol: FN1///FN

Gen-ID: 2335

UniProt: P02751