Desmoglein 1 Antikörper
Kurzübersicht für Desmoglein 1 Antikörper (ABIN6296099)
Target
Alle Desmoglein 1 (DSG1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- Mouse anti-Human Desmoglein 1 Antibody / DSG1 [Sodium Azide Free]
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Spezifität
- Cell surface
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Aufreinigung
- A recombinant protein corresponding to the intracellular domain of human Desmoglein 1 was used as the immunogen for the Desmoglein antibody.
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Immunogen
- A recombinant protein corresponding to the intracellular domain of human Desmoglein 1 was used as the immunogen for the Desmoglein antibody.
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Applikationshinweise
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FACS: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
WB: 0.5-1 μg/mL
Immunoprecipitation: suitable -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- In 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Desmoglein 1 (DSG1)
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Andere Bezeichnung
- Desmoglein-1
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Hintergrund
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Target Description: Desmoglein 1 (DSG1) is a member of the desmosomal cadherin family. Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1, Dsg2, Dsg3, and Dsg4 isoforms. Within the desmosome, the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 1 is synthesized exclusively in the suprabasal layers. Intact and functionally active desmoglein 1 is essential to epidermal integrity.
Gene Symbol: DSG1///CDHF4
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Gen-ID
- 1828
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UniProt
- Q02413
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Pathways
- Cell-Cell Junction Organization
Target
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