CD5 Antikörper

Produktnummer ABIN6296063

Der Maus Monoklonal anti-CD5 Antikörper wird verwendet zum Nachweis von CD5 in Proben von Human, Ratte, Rind (Kuh), Kaninchen, Pferd, Schwein, Affe, Huhn und Meerschweinchen. Er wurde validiert für FACS, WB, IHC und IF.

Kurzübersicht für CD5 Antikörper (ABIN6296063)

Target: CD5

Reaktivität: Human, Ratte, Rind (Kuh), Kaninchen, Pferd, Schwein, Affe, Huhn, Meerschweinchen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD5 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-CD5 Antikörper

Verwendungszweck: Mouse anti-Human/Monkey/Horse/Pig/Rabbit/Cow/Rat/Guinea Pig/Chicken CD5 Antibody [Sodium Azide Free]

Spezifität: Cell surface

Aufreinigung: A peptide from the intracellular region of the human protein was used as the immunogen for this CD5 antibody.

Immunogen: A peptide from the intracellular region of the human protein was used as the immunogen for this CD5 antibody.

Anwendungsinformationen

Applikationshinweise: Western blot: 1-2 μg/mL
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu CD5

Target: CD5

Andere Bezeichnung: T-cell surface glycoprotein CD5

Hintergrund:

Target Description: Recognizes a 67 kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95 % of thymocytes and 72 % of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10 %) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.

Gene Symbol: CD5///LEU1

Gen-ID: 921

UniProt: P06127