RNMT Antikörper

Produktnummer ABIN6296037

Dieses Anti-RNMT-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von RNMT in IHC, IF und FACS. Geeignet für Human, Ratte, Rind (Kuh), Hund und Hamster.

Kurzübersicht für RNMT Antikörper (ABIN6296037)

Target: RNMT (RNA Guanine-7 Methyltransferase (RNMT))

Reaktivität: Human, Ratte, Rind (Kuh), Hund, Hamster

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RNMT Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-RNMT Antikörper

Verwendungszweck: Mouse anti-Human/Cow/Dog/Hamster/Rat TAG-72 Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic and cell surface

Aufreinigung: A membrane-enriched fraction of a human breast carcinoma liver metastasis was used as the immunogen for this TAG-72 antibody.

Immunogen: A membrane-enriched fraction of a human breast carcinoma liver metastasis was used as the immunogen for this TAG-72 antibody.

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu RNMT

Target: RNMT (RNA Guanine-7 Methyltransferase (RNMT))

Andere Bezeichnung: mRNA cap guanine-N7 methyltransferase  

Hintergrund:

Target Description: Recognizes an oncofetal antigen of 220 kDa, identified as a Tumor-associated glycoprotein (TAG-72) with properties of a mucin. This mAb defines the mucin-carried sialylated-Tn epitope. TAG72 is usually expressed by adenocarcinomas, but is negative in mesotheliomas. Studies have reported that this antibody has 80 % sensitivity and 93 % specificity for pulmonary adenocarcinoma. Therefore, TAG72 is a useful marker to distinguish between mesothelioma and adenocarcinoma. However, false positive reactions can occur so results must be interpreted with the utmost caution. This antibody may be useful in the differentiation of non-small cell carcinomas from small cell carcinomas of the lung. The combined use of anti-TAG72 and anti-GCDFP-15 is valuable in the diagnosis of apocrine carcinoma.

Gene Symbol: tag-72  C25A1.3

Gen-ID: 182875

UniProt: Q9XVS1