CD81 Antikörper

Produktnummer ABIN6295927

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CD81 in FACS, WB, IHC, IF und Func. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für CD81 Antikörper (ABIN6295927)

Target: CD81

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD81 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Functional Studies (Func)

Produktdetails anti-CD81 Antikörper

Verwendungszweck: Mouse anti-Human/Mouse/Rat CD81 Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic, membranous

Aufreinigung: A B-cell line derived from a Burkitt lymphoma was used as the immunogen for the CD81 antibody.

Immunogen: A B-cell line derived from a Burkitt lymphoma was used as the immunogen for the CD81 antibody.

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
WB: 0.5-1 μg/mL
Functional Studies: order BSA free formulation
IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu CD81

Target: CD81

Andere Bezeichnung: CD81 antigen

Hintergrund:

Target Description: This mAb recognizes a protein of 26 kDa, identified as CD81 (Workshop VI, Code CD81.1). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.

Gene Symbol: CD81///TAPA1///TSPAN28

Gen-ID: 975

UniProt: P60033

Pathways: Inositol Metabolic Process, Hepatitis C