USP14 Antikörper (N-Term)

Produktnummer ABIN6295499

Der Maus Monoklonal Anti-USP14-Antikörper wurde für validiert. Er ist geeignet, USP14 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für USP14 Antikörper (N-Term) (ABIN6295499)

Target: USP14 (Ubiquitin Specific Peptidase 14 (USP14))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser USP14 Antikörper ist unkonjugiert

Applikation: Bitte anfragen

Produktdetails anti-USP14 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Mouse Anti-USP14 (N-term) Antibody

Immunogen: Purified His-tagged USP14 protein was used to produced this monoclonal antibody.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C (short-term), -20°C (long-term)

Details zu USP14

Target: USP14 (Ubiquitin Specific Peptidase 14 (USP14))

Andere Bezeichnung: USP14

Hintergrund:

Target Description: Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation (ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions (NMJs).

Gene Symbol: USP14

Gen-ID: 9097

UniProt: P54578