TIMP2 Antikörper (N-Term)

Produktnummer ABIN6295483

Dieses Maus Monoklonal-Antikörper erkennt spezifisch TIMP2 in WB, IF und IHC (fp). Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für TIMP2 Antikörper (N-Term) (ABIN6295483)

Target: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Reaktivität: Human, Ratte, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TIMP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-TIMP2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Mouse anti-Human/Mouse/Rat TIMP2 Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic, cell surface, secreted

Aufreinigung: An amino acid sequence from the N-terminal region of the human protein was used as the immunogen for this TIMP2 antibody.

Immunogen: An amino acid sequence from the N-terminal region of the human protein was used as the immunogen for this TIMP2 antibody.

Anwendungsinformationen

Applikationshinweise: IHC (FFPE): 0.5-1 μg/mL for 30 min at RT
WB: 0.5-1 μg/mL
IF: 1-2 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu TIMP2

Target: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Andere Bezeichnung: Metalloproteinase inhibitor 2

Hintergrund:

Target Description: It recognizes a protein of 21 kDa, identified as tissue inhibitor of metalloproteinases 2 (TIMP2). It is closely related to TIMP1 and shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP9 or gelatinase B). TIMP2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

Gene Symbol: TIMP2

Gen-ID: 7077

UniProt: P16035

Pathways: cAMP Metabolic Process