CLTA Antikörper (N-Term)

Produktnummer ABIN6295474

Dieses Maus Monoklonal-Antikörper erkennt spezifisch CLTA in WB, IHC, FACS und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CLTA Antikörper (N-Term) (ABIN6295474)

Target: CLTA (Clathrin, Light Chain A (CLTA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CLTA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Produktdetails anti-CLTA Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Mouse anti-Human Clatherin Light Chain Antibody (LCA/LCB) [Sodium Azide Free]

Spezifität: Cytoplasmic

Aufreinigung: A recombinant N-terminal protein fragment from human Clathrin light chain was used as the immunogen for the Clathrin Light Chain antibody.

Immunogen: A recombinant N-terminal protein fragment from human Clathrin light chain was used as the immunogen for the Clathrin Light Chain antibody.

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
WB: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu CLTA

Target: CLTA (Clathrin, Light Chain A (CLTA))

Andere Bezeichnung: Clathrin light chain A

Hintergrund:

Target Description: Recognizes proteins of 31-44 kDa, which are identified as Clathrin Light Chains (both A & B). Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. LCA and LCB are encoded by two discrete genes. They share only 60 % homology, and have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms.

Gene Symbol: CLTA///CLTB

UniProt: P09496, P09497

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, EGFR Downregulation