AIRE Antikörper (Center)
Kurzübersicht für AIRE Antikörper (Center) (ABIN6295388)
Target
Alle AIRE Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 64-92, Center
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Verwendungszweck
- Rabbit Anti-AIRE (Center) Antibody
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Immunogen
- This AIRE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the Central region of human AIRE.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- AIRE (Autoimmune Regulator (AIRE))
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Andere Bezeichnung
- AIRE
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Hintergrund
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Target Description: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript predicted to be a candidate for nuclear-mediated decay (NMD). Defects in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).
Gene Symbol: AIRE
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Gen-ID
- 326
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UniProt
- O43918
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Pathways
- Chromatin Binding
Target
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