LDL Antikörper (Center)
Kurzübersicht für LDL Antikörper (Center) (ABIN6295353)
Target
Alle LDL Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 391-419, Center
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Verwendungszweck
- Rabbit Anti-LDLR (Center) Antibody
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Immunogen
- This LDLR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-419 amino acids from the Central region of human LDLR.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- LDL (Low Density Lipoprotein (LDL))
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Andere Bezeichnung
- LDL
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Hintergrund
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Target Description: The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place.
Gene Symbol: LDLR
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Gen-ID
- 3949
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UniProt
- P01130
Target
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