CSE1L Antikörper (C-Term)
Kurzübersicht für CSE1L Antikörper (C-Term) (ABIN6295024)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 55-84, C-Term
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Verwendungszweck
- Rabbit Anti-Cellular Apoptosis Susceptibility (C-term) Antibody
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Immunogen
- This Cellular Apoptosis Susceptibility antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-84 amino acids from the C-terminal region of human Cellular Apoptosis Susceptibility.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- CSE1L (Chromosome Segregation 1-Like (CSE1L))
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Andere Bezeichnung
- Cellular Apoptosis Susceptibility
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Hintergrund
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Target Description: Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. CSE1L binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, CSE1L may play a role both in apoptosis and in cell proliferation.
Gene Symbol: CSE1L
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Gen-ID
- 1434
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UniProt
- P55060
Target
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