Pyruvate Kinase Antikörper (C-Term)
Kurzübersicht für Pyruvate Kinase Antikörper (C-Term) (ABIN6294981)
Target
Alle Pyruvate Kinase (PK) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 476-505, C-Term
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Verwendungszweck
- Rabbit Anti-Pyruvate Kinase (PKM2) (C-term) Antibody
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Immunogen
- This Pyruvate Kinase (PKM2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-505 amino acids from the C-terminal region of human Pyruvate Kinase (PKM2).
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C (short-term), -20°C (long-term)
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- Pyruvate Kinase (PK)
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Andere Bezeichnung
- Pyruvate Kinase
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Hintergrund
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Target Description: There are 4 isozymes of pyruvate kinase in mammals: L, R, M1 and M2. PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.
Gene Symbol: PKM
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Gen-ID
- 5315
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UniProt
- P14618
Target
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