ESR2 Antikörper (C-Term)

Produktnummer ABIN6294672

Dieses Anti-ESR2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von ESR2 in WB, IHC, IF und FACS. Geeignet für Human, Maus, Ratte, Schaf, Schwein, Pferd und Affe.

Kurzübersicht für ESR2 Antikörper (C-Term) (ABIN6294672)

Target: ESR2 (Estrogen Receptor 2 (ESR2))

Reaktivität: Human, Maus, Ratte, Schaf, Schwein, Pferd, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ESR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-ESR2 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Mouse anti-Human/Monkey/Mouse/Rat/Pig/Horse/Sheep Estrogen Receptor beta Antibody [Sodium Azide Free]

Spezifität: Predominantly nuclear

Aufreinigung: The C-terminus fragment of recombinant human Estrogen Receptor beta protein was used as the immunogen for this antibody.

Immunogen: The C-terminus fragment of recombinant human Estrogen Receptor beta protein was used as the immunogen for this antibody.

Anwendungsinformationen

Applikationshinweise: FACS: 0.5-1 μg/10e6 cells
IF: 1-2 μg/mL
WB: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu ESR2

Target: ESR2 (Estrogen Receptor 2 (ESR2))

Andere Bezeichnung: Estrogen receptor beta

Hintergrund:

Target Description: Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including alpha and beta, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ER alpha and beta are differentially activated by various ligands. Ligand interaction triggers a cascade of events, including dissociation from heat shock proteins, recepter dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ER alpha and beta may be regulated by distinct mechanisms even though they share many functional characteristics.

Gene Symbol: ESR2///ESTRB///NR3A2

Gen-ID: 2100

UniProt: Q92731

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling