Ubiquitin Hydrolase Isozyme L1 (C-Term) Antikörper

Produktnummer ABIN6294653

Der Maus Monoklonal anti-Ubiquitin Hydrolase Isozyme L1 Antikörper wird verwendet zum Nachweis von Ubiquitin Hydrolase Isozyme L1 in Proben von Human, Ratte, Rind (Kuh), Maus und Schwein. Er wurde validiert für IHC und WB.

Kurzübersicht für Ubiquitin Hydrolase Isozyme L1 (C-Term) Antikörper (ABIN6294653)

Target: Ubiquitin Hydrolase Isozyme L1

Reaktivität: Human, Ratte, Rind (Kuh), Maus, Schwein

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Produktdetails

Bindungsspezifität: C-Term

Verwendungszweck: Mouse anti-Human/Mouse/Rat/Cow/Pig PGP9.5 Antibody UchL1 [Sodium Azide Free]

Spezifität: Cytoplasmic

Aufreinigung: Native protein from brain was used as the immunogen for this PGP9.5 antibody.

Immunogen: Native protein from brain was used as the immunogen for this PGP9.5 antibody.

Anwendungsinformationen

Applikationshinweise: WB: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Antigendetails

Target: Ubiquitin Hydrolase Isozyme L1

Hintergrund:

Target Description: This antibody specifically reacts with a protein of 20-30 kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. PGP9.5 antibody has been used to show the protein to be a useful prognostic indicator of colorectal, pancreatic and gall bladder cancer. A mutation in the gene is believed to cause a form of Parkinson's disease.

Gene Symbol: UCHL1

Gen-ID: 7345

UniProt: P09936