TFF1 Antikörper (C-Term)

Produktnummer ABIN6294638

Der Maus Monoklonal Anti-TFF1-Antikörper wurde für IHC und IF validiert. Er ist geeignet, TFF1 in Proben von Human zu detektieren.

Kurzübersicht für TFF1 Antikörper (C-Term) (ABIN6294638)

Target: TFF1 (Trefoil Factor 1 (TFF1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TFF1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-TFF1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Mouse anti-Human TFF1 Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic

Aufreinigung: A C-terminus peptide was used as the immunogen for the TFF1 antibody.

Immunogen: A C-terminus peptide was used as the immunogen for the TFF1 antibody.

Anwendungsinformationen

Applikationshinweise: Immunofluorescence: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu TFF1

Target: TFF1 (Trefoil Factor 1 (TFF1))

Andere Bezeichnung: Trefoil factor 1

Hintergrund:

Target Description: TFF1/Breast cancer estrogen inducible protein pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. TFF1/pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60 % of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. TFF1 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract.

Gene Symbol: TFF1///BCEI///PS2

Gen-ID: 7031

UniProt: P04155

Pathways: EGFR Signaling Pathway