PTH Antikörper (C-Term)

Produktnummer ABIN6294631

Dieser Maus Monoklonal Antikörper detektiert spezifisch PTH in IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PTH Antikörper (C-Term) (ABIN6294631)

Target: PTH (Parathyroid Hormone (PTH))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PTH Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Produktdetails anti-PTH Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Mouse anti-Human Parathyroid Hormone Antibody [IHC only]

Spezifität: Cytoplasmic and secreted

Aufreinigung: A C-terminal partial recombinant protein from the human protein was used as the immunogen for the Parathyroid Hormone antibody.

Immunogen: A C-terminal partial recombinant protein from the human protein was used as the immunogen for the Parathyroid Hormone antibody.

Anwendungsinformationen

Applikationshinweise: Prediluted format : incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu PTH

Target: PTH (Parathyroid Hormone (PTH))

Andere Bezeichnung: Parathyroid hormone

Substanzklasse: Hormone

Hintergrund:

Target Description: Parathyroid hormone (PTH), parathormone or parathyrin, is secreted by the chief cells of the parathyroid glands as a polypeptide containing 84 amino acids, yet effective hormone-receptor interaction requires solely the 34-N-terminal amino acids. While PTH acts to increase the concentration of ionic calcium (Ca2+) in the blood, calcitonin, a hormone produced by the parafollicular cells (C cells) of the thyroid gland, acts to decrease ionic calcium concentration. PTH essentially acts to increase the concentration of calcium in the blood by acting upon the parathyroid hormone 1 receptor, which is present at high levels in bone and kidney, and the parathyroid hormone 2 receptor, which is present at high levels in the central nervous system, pancreas, testis, and placenta. [Wiki]

Gene Symbol: PTH

Gen-ID: 5741

UniProt: P01270

Pathways: cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process