KRT15 Antikörper (C-Term)

Produktnummer ABIN6294627

Dieses Anti-KRT15-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von KRT15 in WB, IHC, FACS und IF. Geeignet für Human, Ratte und Rind (Kuh).

Kurzübersicht für KRT15 Antikörper (C-Term) (ABIN6294627)

Target: KRT15 (Keratin 15 (KRT15))

Reaktivität: Human, Ratte, Rind (Kuh)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KRT15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Produktdetails anti-KRT15 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Mouse anti-Human/Rat/Cow Cytokeratin 15 Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic

Aufreinigung: A 17 amino acid sequence from the C- terminal of human CK15 was used as the immunogen for the Keratin 15 antibody.

Immunogen: A 17 amino acid sequence from the C- terminal of human CK15 was used as the immunogen for the Keratin 15 antibody.

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
WB: 0.5-1 μg/mL
Immunohistochemistry (FFPE & Frozen): 0.5-1 μg/mL for 30 min at RT

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu KRT15

Target: KRT15 (Keratin 15 (KRT15))

Andere Bezeichnung: Keratin, type I cytoskeletal 15

Hintergrund:

Target Description: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratin 15 is a type I keratin which is expressed only in basal keratinocytes in stratified epithelia and does not appear to have a natural type II expression partner. Keratin 15 is down regulated in activated keratinocytes. Cytokeratin 15 is a specific marker of stem cells of the hair-follicle bulge and may be a useful marker for diagnosis between basal cell carcinoma (BCC) and trichoepithelioma. Trichoblastoma are benign neoplasms of follicular differentiation frequently found in nevus sebaceous. Many morphologic features are shared with nodular basal cell carcinoma, sometimes rendering a diagnosis difficult. Trichoblastoma and BCC show variable expression of Cytokeratin 15 and Cytokeratin 19, and absence of hair keratins.

Gene Symbol: KRT15///KRTB

Gen-ID: 3866

UniProt: P19012