Filaggrin Antikörper (AA 998-1104)

Produktnummer ABIN6294618

Dieses Anti-Filaggrin-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Filaggrin in IHC, IF und FACS. Geeignet für Human.

Kurzübersicht für Filaggrin Antikörper (AA 998-1104) (ABIN6294618)

Target: Filaggrin (FLG)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Filaggrin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-Filaggrin Antikörper

Bindungsspezifität: AA 998-1104

Verwendungszweck: Mouse anti-Human Filaggrin Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic

Aufreinigung: Amino acids 998-1104 of human FLG were used as the immunogen for this Filaggrin antibody.

Immunogen: Amino acids 998-1104 of human FLG were used as the immunogen for this Filaggrin antibody.

Anwendungsinformationen

Applikationshinweise: FACS: 0.5-1 μg/10^6 cells in 0.1ml
IF: 1-2 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu Filaggrin

Target: Filaggrin (FLG)

Andere Bezeichnung: Filaggrin

Hintergrund:

Target Description: Filaggrin (FLG) is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple Filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional Filaggrin molecules. Active Filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.

Gene Symbol: FLG

Gen-ID: 2312

UniProt: P20930

Pathways: Sensory Perception of Sound, Stem Cell Maintenance