Elastase 3B Antikörper (AA 82-238)

Produktnummer ABIN6294592

Dieser Maus Monoklonal Antikörper erkennt spezifisch Elastase 3B in ELISA, Coat, IF, FACS und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für Elastase 3B Antikörper (AA 82-238) (ABIN6294592)

Target: Elastase 3B (ELA3B) (Elastase 3B, Pancreatic (ELA3B))

Reaktivität: Human, Ratte, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Elastase 3B Antikörper ist unkonjugiert

Applikation: ELISA, Coating (Coat), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Elastase 3B Antikörper

Bindungsspezifität: AA 82-238

Verwendungszweck: Mouse anti-Human/Mouse/Rat CELA3B Antibody / Elastase 3B [Sodium Azide Free]

Spezifität: Cytoplasmic

Aufreinigung: A partial recombinant protein (aa 82-238) was used as the immunogen for the Elastase 3B antibody.

Immunogen: A partial recombinant protein (aa 82-238) was used as the immunogen for the Elastase 3B antibody.

Anwendungsinformationen

Applikationshinweise: ELISA: 2-4 μg/mL, order BSA free format for coating
FACS: 0.5-1 μg/10^6 cells in 0.1ml
IF: 1-2 μg/mL
IHC-P: 1-2 μg/mL for 30 min at RT

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu Elastase 3B

Target: Elastase 3B (ELA3B) (Elastase 3B, Pancreatic (ELA3B))

Andere Bezeichnung: Chymotrypsin-like elastase family member 3B

Hintergrund:

Target Description: Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six genes which encode the structurally similar proteins: Elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, 3B has little elastolytic activity. Like most of the human elastases, 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. It may also function in the intestinal transport and metabolism of cholesterol. Elastases 3A/B have been referred to as Protease E and as Elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays.

Gene Symbol: CELA3B///ELA3B

Gen-ID: 23436

UniProt: P08861