Elastase 3B Antikörper (AA 82-238)

Produktnummer ABIN6294592

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Elastase 3B in ELISA, Coat, IF, FACS und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für Elastase 3B Antikörper (AA 82-238) (ABIN6294592)

Target: Elastase 3B (ELA3B) (Elastase 3B, Pancreatic (ELA3B))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Elastase 3B Antikörper ist unkonjugiert

Applikation: ELISA, Coating (Coat), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Elastase 3B Antikörper

Bindungsspezifität: AA 82-238

Verwendungszweck: Mouse anti-Human/Mouse/Rat CELA3B Antibody / Elastase 3B [Sodium Azide Free]

Spezifität: Cytoplasmic

Aufreinigung: A partial recombinant protein (aa 82-238) was used as the immunogen for the Elastase 3B antibody.

Immunogen: A partial recombinant protein (aa 82-238) was used as the immunogen for the Elastase 3B antibody.

Anwendungsinformationen

Applikationshinweise: ELISA: 2-4 μg/mL, order BSA free format for coating
FACS: 0.5-1 μg/10^6 cells in 0.1ml
IF: 1-2 μg/mL
IHC-P: 1-2 μg/mL for 30 min at RT

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu Elastase 3B

Target: Elastase 3B (ELA3B) (Elastase 3B, Pancreatic (ELA3B))

Andere Bezeichnung: Chymotrypsin-like elastase family member 3B

Hintergrund:

Target Description: Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six genes which encode the structurally similar proteins: Elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, 3B has little elastolytic activity. Like most of the human elastases, 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. It may also function in the intestinal transport and metabolism of cholesterol. Elastases 3A/B have been referred to as Protease E and as Elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function in clinical assays.

Gene Symbol: CELA3B///ELA3B

Gen-ID: 23436

UniProt: P08861