TIMP2 Antikörper (AA 56-66)

Produktnummer ABIN6294556

Dieses Maus Monoklonal-Antikörper erkennt spezifisch TIMP2 in WB, IF und IHC (fp). Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus, Rind (Kuh), Zebrafisch (Danio rerio), Kaninchen und Meerschweinchen.

Kurzübersicht für TIMP2 Antikörper (AA 56-66) (ABIN6294556)

Target: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Zebrafisch (Danio rerio), Kaninchen, Meerschweinchen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TIMP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Produktdetails anti-TIMP2 Antikörper

Bindungsspezifität: AA 56-66

Verwendungszweck: Mouse anti-Human/Mouse/Rat/Guinea pig/Rabbit/Cow/Zebrafish TIMP2 Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic, cell surface, secreted

Aufreinigung: Amino acids 56-66 (DSGNDIYGNPI) from the human protein were used as the immunogen for this TIMP-2 antibody.

Immunogen: Amino acids 56-66 (DSGNDIYGNPI) from the human protein were used as the immunogen for this TIMP-2 antibody.

Anwendungsinformationen

Applikationshinweise: IHC (FFPE): 0.5-1 μg/mL for 30 min at RT
WB: 0.5-1 μg/mL
IF: 1-2 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu TIMP2

Target: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Andere Bezeichnung: Metalloproteinase inhibitor 2

Hintergrund:

Target Description: It recognizes a protein of 21 kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

Gene Symbol: TIMP2

Gen-ID: 7077

UniProt: P16035

Pathways: cAMP Metabolic Process