p63 Antikörper (AA 5-17)

Produktnummer ABIN6294546

Dieses Anti-p63-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von p63 in WB, IHC, IF und FACS. Geeignet für Human, Maus, Ratte und Rind (Kuh).

Kurzübersicht für p63 Antikörper (AA 5-17) (ABIN6294546)

Target: p63 (TP63) (Tumor Protein P63 (TP63))

Reaktivität: Human, Maus, Ratte, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser p63 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-p63 Antikörper

Bindungsspezifität: AA 5-17

Verwendungszweck: Rabbit anti-Human/Mouse/Rat/Cow p40 Antibody [Sodium Azide Free]

Spezifität: Nuclear

Aufreinigung: Amino acids ENNAQTQFSEPQY (aa 5-17) of human p40 / p63 delta were used as the immunogen for this antibody.

Immunogen: Amino acids ENNAQTQFSEPQY (aa 5-17) of human p40 / p63 delta were used as the immunogen for this antibody.

Anwendungsinformationen

Applikationshinweise: FACS: 0.5-1 μg/10e6 cells
IF: 1-2 μg/mL
WB: 0.5-1 μg/mL
IHC (FFPE): 1-2 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu p63

Target: p63 (TP63) (Tumor Protein P63 (TP63))

Andere Bezeichnung: Tumor protein 63

Hintergrund:

Target Description: p40 (p63 delta) is a marker recently determined to be highly specific for squamous basal cells in the immunohistochemistry (IHC) application. The current more routinely recommended marker, p63, appears to have less specificity compared to p40, especially on squamous cell tumors. The ability to differentiate between lung adenocarcinoma vs. squamous cell carcinoma is difficult and has bearing on the different therapeutic avenues for each subtype treatment. p40 antibody 's ability to distinguish between the tumor types appears to be superior when compared to p63. The ability to utilize a p40 antibody probe as a squamous cell marker bolsters its use for future sub-classification of lung cancers, especially by immunohistochemical techniques.

Gene Symbol: TP63///KET///P63///P73H///P73L///TP73L

Gen-ID: 8626

UniProt: Q9H3D4