FTL Antikörper (AA 38-165)
Kurzübersicht für FTL Antikörper (AA 38-165) (ABIN6294503)
Target
Alle FTL Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 38-165
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Verwendungszweck
- Mouse anti-Human Ferritin Antibody (light chain specific) [Sodium Azide Free]
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Spezifität
- Cytoplasmic
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Aufreinigung
- Amino acids 38-165 of human FTL were used as the immunogen for this Ferritin antibody (light chain specific).
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Immunogen
- Amino acids 38-165 of human FTL were used as the immunogen for this Ferritin antibody (light chain specific).
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Applikationshinweise
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Western blot: 1-2 μg/mL
FACS: 0.5-1 μg/10^6 cells
IF: 1-2 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 min at RT (1) -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- FTL (Ferritin, Light Polypeptide (FTL))
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Andere Bezeichnung
- Ferritin light chain
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Hintergrund
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Target Description: Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.
Gene Symbol: FTL
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Gen-ID
- 2512
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UniProt
- P02792
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Pathways
- Transition Metal Ion Homeostasis
Target
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