Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) Antikörper

Produktnummer ABIN6294492

Dieses Anti--Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von in WB, FACS, IHC und IF. Geeignet für Human, Maus und Ratte.

Kurzübersicht für Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) Antikörper (ABIN6294492)

Target: Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails

Bindungsspezifität: AA 356-475

Verwendungszweck: Mouse anti-Human/Mouse/Rat SPTBN2 Antibody / Spectrin beta III [Sodium Azide Free]

Spezifität: Cell surface

Aufreinigung: Human recombinant partial protein corresponding to amino acids 356-475 was used as the immunogen for this Spectrin beta III antibody.

Immunogen: Human recombinant partial protein corresponding to amino acids 356-475 was used as the immunogen for this Spectrin beta III antibody.

Anwendungsinformationen

Applikationshinweise: FACS: 0.5-1 μg/10^6 cells in 0.1ml
IF: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 min at RT
WB: 0.5-1 μg/mL,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Antigendetails

Target: Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)

Andere Bezeichnung: Spectrin beta chain, non-erythrocytic 2

Hintergrund:

Target Description: Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Spectrin alpha and spectrin beta are present in erythrocytes, whereas spectrin alphaII (fodrin alpha) and spectrin betaI (fodrin beta) are present in other somatic cells. SPTBN2/Spectrin betaIII is highly homologous to both spectrin betaI and spectrin betaII. SPTBN2 is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta.

Gene Symbol: SPTBN2///KIAA0302///SCA5

Gen-ID: 6712

UniProt: O15020

Pathways: Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis