EpCAM Antikörper (AA 20-60)
Kurzübersicht für EpCAM Antikörper (AA 20-60) (ABIN6294377)
Target
Alle EpCAM (EPCAM) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 20-60
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Verwendungszweck
- Rabbit anti-Human/rat Recombinant EpCAM Antibody [Sodium Azide Free]
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Spezifität
- Cell surface, cytoplasmic
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Aufreinigung
- A portion of amino acids 20-60 was used as the immunogen for the recombinant EpCAM antibody.
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Immunogen
- A portion of amino acids 20-60 was used as the immunogen for the recombinant EpCAM antibody.
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Applikationshinweise
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Western blot: 0.5-1 μg/mL
IF: 1-2 μg/mL
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT
Prediluted IHC only format: incubate for 30 min at RT (1)
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- In 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))
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Andere Bezeichnung
- Epithelial cell adhesion molecule
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Hintergrund
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Target Description: Recognizes a 40-43 kDa transmembrane epithelial glycoprotein, identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). EpCAM is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. It is also useful in distinguishing serous carcinomas of the ovary from mesothelioma. This epithelial antigen plays an important role as a tumor-cell marker in lymph nodes from patients with esophageal carcinoma otherwise classified as node-negative. Epithelial antigen has also been suggested as a discriminator between basal cell and baso-squamous carcinomas, and squamous cell carcinoma of the skin.
Gene Symbol: EPCAM///GA733-2///M1S2///M4S1///MIC18///TACSTD1///TROP1
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Gen-ID
- 4072
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UniProt
- P16422
Target
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