TIMP3 Antikörper (AA 175-211)

Produktnummer ABIN6294338

Der Kaninchen Polyklonal Anti-TIMP3-Antikörper wurde für WB, IHC, IP, FACS und IF validiert. Er ist geeignet, TIMP3 in Proben von Human, Maus, Ratte, Rind (Kuh), Hund und Pferd zu detektieren.

Kurzübersicht für TIMP3 Antikörper (AA 175-211) (ABIN6294338)

Target: TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIMP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS), Immunofluorescence (IF)

Produktdetails anti-TIMP3 Antikörper

Bindungsspezifität: AA 175-211

Verwendungszweck: Rabbit anti-Human/Mouse/Rat/Horse/Cow/Dog TIMP3 Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic

Aufreinigung: Amino acids 175-211 of human TIMP3 Ab was used as the immunogen for this antibody (100% homologous in cow, dog and horse, and 94% homologous in mouse and rat).

Immunogen: Amino acids 175-211 of human TIMP3 Ab was used as the immunogen for this antibody (100% homologous in cow, dog and horse, and 94% homologous in mouse and rat).

Anwendungsinformationen

Applikationshinweise: FACS: use antibody at 0.5-1 μg/million cells
IF: 1-2 μg/mL
WB: 0.5-1 μg/mL
IP: 1-2 μg/500 μg protein lysate
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS ( pH 7.4), BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu TIMP3

Target: TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))

Andere Bezeichnung: Metalloproteinase inhibitor 3

Hintergrund:

Target Description: TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP 's inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes.

Gene Symbol: TIMP3

Gen-ID: 7078

UniProt: P35625