LGALS1/Galectin 1 Antikörper (AA 12-108)

Produktnummer ABIN6294291

Dieses Anti-LGALS1/Galectin 1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von LGALS1/Galectin 1 in WB, IHC, ELISA, FACS, IF und Coat. Geeignet für Human.

Kurzübersicht für LGALS1/Galectin 1 Antikörper (AA 12-108) (ABIN6294291)

Target: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LGALS1/Galectin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Coating (Coat)

Produktdetails anti-LGALS1/Galectin 1 Antikörper

Bindungsspezifität: AA 12-108

Verwendungszweck: Mouse anti-Human Galectin 1 Antibody [Sodium Azide Free]

Spezifität: Cytoplasmic, secreted

Aufreinigung: A human partial recombinant protein corresponding to amino acids 12-108 was used as the immunogen for the Galectin 1 antibody.

Immunogen: A human partial recombinant protein corresponding to amino acids 12-108 was used as the immunogen for the Galectin 1 antibody.

Anwendungsinformationen

Applikationshinweise: ELISA: 2-4 μg/mL, order the BSA-free formulation for coating
IF: 1-2 μg/mL
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
WB: 0.5-1 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Details zu LGALS1/Galectin 1

Target: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Andere Bezeichnung: Galectin-1

Hintergrund:

Target Description: Galectin 1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14 kDa participating in a variety of normal and pathological processes, including cancer progression. Galectin 1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin 1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 Molecules present on the surface of lymphocytes. Galectin 1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival.

Gene Symbol: LGALS1

Gen-ID: 3956

UniProt: P09382

Pathways: Carbohydrate Homeostasis