Transforming Protein Myb (AA 119-135) Antikörper

Produktnummer ABIN6294290

Der Maus Monoklonal anti-Transforming Protein Myb Antikörper wird verwendet zum Nachweis von Transforming Protein Myb in Proben von Human. Er wurde validiert für FACS und IF.

Kurzübersicht für Transforming Protein Myb (AA 119-135) Antikörper (ABIN6294290)

Target: Transforming Protein Myb

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF)

Produktdetails

Bindungsspezifität: AA 119-135

Verwendungszweck: Mouse anti-Human c-Myb Antibody [Sodium Azide Free]

Spezifität: Nuclear

Aufreinigung: Amino acids 119-135 (RRKVEQEGYPQESSKAG) from the human protein were used as the immunogen for this c-Myb antibody.

Immunogen: Amino acids 119-135 (RRKVEQEGYPQESSKAG) from the human protein were used as the immunogen for this c-Myb antibody.

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: In 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Antigendetails

Target: Transforming Protein Myb

Hintergrund:

Target Description: The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.

Gene Symbol: V-MYB

UniProt: P01104