CRYGB Antikörper

Produktnummer ABIN6292463

Der Kaninchen Polyklonal Anti-CRYGB-Antikörper wurde für WB validiert. Er ist geeignet, CRYGB in Proben von Maus und Ratte zu detektieren.

Kurzübersicht für CRYGB Antikörper (ABIN6292463)

Target: CRYGB (Crystallin, gamma B (CRYGB))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CRYGB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CRYGB Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human CRYGB

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu CRYGB

Target: CRYGB (Crystallin, gamma B (CRYGB))

Andere Bezeichnung: CRYGB

Hintergrund: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation.

Molekulargewicht: 20.908 kDa

Gen-ID: 1419

UniProt: P07316