Der Kaninchen Polyklonal Anti-APRT-Antikörper wurde für WB und IHC validiert. Er ist geeignet, APRT in Proben von Human, Ratte und Maus zu detektieren.
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20C. Avoid freeze / thaw cycles.
Target
APRT
(Adenine Phosphoribosyltransferase (APRT))
Andere Bezeichnung
APRT
Hintergrund
Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.