GIMAP5 Antikörper

Produktnummer ABIN6290420

Der Kaninchen Polyklonal Anti-GIMAP5-Antikörper wurde für WB validiert. Er ist geeignet, GIMAP5 in Proben von Ratte und Maus zu detektieren.

Kurzübersicht für GIMAP5 Antikörper (ABIN6290420)

Target: GIMAP5 (GTPase, IMAP Family Member 5 (GIMAP5))

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GIMAP5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GIMAP5 Antikörper

Aufreinigung: Affinity purification

Immunogen: Recombinant Protein of human GIMAP5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000

Kommentare:

Widely expressed with high levels in lymph node and spleen, High expression found in CD4 and CD8-positive T-cells and monocytes with very low levels in B-lymphocytes, Highly expressed in B-lymphocyte-derived neoplasms

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20C. Avoid freeze / thaw cycles.

Details zu GIMAP5

Target: GIMAP5 (GTPase, IMAP Family Member 5 (GIMAP5))

Andere Bezeichnung: GIMAP5

Hintergrund: This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. This gene encodes an antiapoptotic protein that functions in T-cell survival. Polymorphisms in this gene are associated with systemic lupus erythematosus. Read-through transcription exists between this gene and the neighboring upstream GIMAP1 (GTPase, IMAP family member 1) gene.

Molekulargewicht: 34.846 kDa

Gen-ID: 55340

UniProt: Q96F15

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response