Histone 3 Antikörper (H3K79me2)
Kurzübersicht für Histone 3 Antikörper (H3K79me2) (ABIN6266346)
Target
Alle Histone 3 (H3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- H3K79me2
-
Spezifität
- Di-Methyl-Histone H3 (Lys79)/H3K79me2 Antibody detects endogenous levels of Di-Methyl-Histone H3 only when methylated at Lys79.
-
Homologie
- Horse,Sheep,Rabbit
-
Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
Immunogen
- A synthetic methylated peptide derived from human Di-Methyl-Histone H3 around the methylation site of Lys79.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:500-1:1000, IHC 1:50-1:100, IF/ICC 1:50-1:200, IP 1:50-1:200, CHIP 1:50-1:200, ELISA(peptide) 1:20000-1:40000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
-
Haltbarkeit
- 12 months
-
-
- Histone 3 (H3) (Histone H3 (H3))
-
Andere Bezeichnung
- HIST3H3
-
Hintergrund
-
Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Gene: HIST3H3
-
Molekulargewicht
- 16kDa
-
Gen-ID
- 8290
-
UniProt
- Q16695
Target
-