YTHDF1 Antikörper (N-Term)

Produktnummer ABIN6266080

Produktdetails anti-YTHDF1 Antikörper

Target: YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser YTHDF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: YTHDF1 Antibody detects endogenous levels of total YTHDF1.

Homologie: Pig,Bovine,Horse,Sheep,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human YTHDF1, corresponding to a region within N-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu YTHDF1

Target: YTHDF1 (YTH Domain Family, Member 1 (YTHDF1))

Andere Bezeichnung: YTHDF1 (YTHDF1 Produkte)

Synonyme: fb49c02 antikoerper, zgc:55657 antikoerper, wu:fb49c02 antikoerper, wu:fi19h06 antikoerper, wu:fj87f09 antikoerper, wu:fp06c11 antikoerper, MGC75606 antikoerper, MGC68505 antikoerper, 2210410K23Rik antikoerper, 8030473O16 antikoerper, C20orf21 antikoerper, YTH N(6)-methyladenosine RNA binding protein 1 antikoerper, YTH N(6)-methyladenosine RNA binding protein 1 L homeolog antikoerper, YTH N6-methyladenosine RNA binding protein 1 antikoerper, YTH domain family 1 antikoerper, ythdf1 antikoerper, ythdf1.L antikoerper, YTHDF1 antikoerper, Ythdf1 antikoerper

Hintergrund:

Description: Specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and promotes mRNA translation efficiency (PubMed:24284625, PubMed:26046440, PubMed:26318451). M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in the efficiency of mRNA splicing, processing and stability (PubMed:24284625). Acts as a regulator of mRNA translation efficiency: promotes ribosome loading to m6A-containing mRNAs and interacts with translation initiation factors eIF3 (EIF3A or EIF3B) to facilitate translation initiation (PubMed:26046440).

Gene: YTHDF1

Molekulargewicht: 61kDa

Gen-ID: 54915

UniProt: Q9BYJ9