USP6 Antikörper
Kurzübersicht für USP6 Antikörper (ABIN6265934)
Target
Alle USP6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Spezifität
- USP6 Antibody detects endogenous levels of total USP6
-
Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
-
Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
Immunogen
- A synthesized peptide derived from human USP6
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB 1:1000-3000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
-
Haltbarkeit
- 12 months
-
-
- USP6 (Ubiquitin Specific Peptidase 6 (USP6))
-
Andere Bezeichnung
- USP6
-
Hintergrund
-
Description: Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.
Gene: USP6
-
Molekulargewicht
- 159 kDa
-
Gen-ID
- 9098
-
UniProt
- P35125
Target
-