USP6 Antikörper (C-Term)
Kurzübersicht für USP6 Antikörper (C-Term) (ABIN6265934)
Target
Alle USP6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- USP6 Antibody
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Spezifität
- USP6 Antibody detects endogenous levels of total USP6
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human USP6, corresponding to a region within C-terminal amino acids.
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Isotyp
- IgG
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Applikationshinweise
- IHC 1:50-1:200,WB 1:1000-3000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
- 12 months
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- USP6 (Ubiquitin Specific Peptidase 6 (USP6))
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Andere Bezeichnung
- USP6
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Hintergrund
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Description: Deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. Catalyzes its own deubiquitination. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. Promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. Is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.
Gene: USP6
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Molekulargewicht
- 159 kDa
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Gen-ID
- 9098
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UniProt
- P35125
Target
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