USP51 Antikörper

Produktnummer ABIN6265932

Produktdetails anti-USP51 Antikörper

Target: USP51 (Ubiquitin Specific Peptidase 51 (USP51))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser USP51 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: USP51 Antibody detects endogenous levels of total USP51

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human USP51

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C.Stable for 12 months from date of receipt

Haltbarkeit: 12 months

Details zu USP51

Target: USP51 (Ubiquitin Specific Peptidase 51 (USP51))

Andere Bezeichnung: USP51 (USP51 Produkte)

Synonyme: AV136873 antikoerper, ubiquitin specific peptidase 51 antikoerper, ubiquitin specific protease 51 antikoerper, USP51 antikoerper, Usp51 antikoerper

Hintergrund:

Description: Specifically deubiquitinates 'Lys-14' (H2AK13Ub) and 'Lys-16'(H2AK15Ub) of histone H2A regulating the DNA damage response at double-strand breaks (DSBs) (PubMed:27083998). USP51 is recruited to chromatin after DNA damage and regulates the dynamic assembly/disassembly of TP53BP1 and BRCA1. Exhibits also activity for 'Lys-27' or 'Lys-63'-linked di-ubiquitin (PubMed:27083998).

Gene: USP51

Molekulargewicht: 80 kDa

Gen-ID: 158880

UniProt: Q70EK9