USP51 Antikörper
Kurzübersicht für USP51 Antikörper (ABIN6265932)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
- 
    - 
                                            Spezifität
- USP51 Antibody detects endogenous levels of total USP51
- 
                                            Kreuzreaktivität
- Human, Maus, Ratte (Rattus)
- 
                                            Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 
                                            Immunogen
- A synthesized peptide derived from human USP51
- 
                                            Isotyp
- IgG
 
- 
                                            
- 
    
- 
    - 
                                            Applikationshinweise
- WB 1:1000-3000
- 
                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
- 
                                            
- 
    - 
                                            Format
- Liquid
- 
                                            Konzentration
- 1 mg/mL
- 
                                            Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 
                                            Konservierungsmittel
- Sodium azide
- 
                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            Lagerung
- -20 °C
- 
                                            Informationen zur Lagerung
- Store at -20 °C.Stable for 12 months from date of receipt
- 
                                            Haltbarkeit
- 12 months
 
- 
                                            
- 
    - USP51 (Ubiquitin Specific Peptidase 51 (USP51))
- 
                                            Andere Bezeichnung
- USP51
- 
                                            Hintergrund
- 
                        Description: Specifically deubiquitinates 'Lys-14' (H2AK13Ub) and 'Lys-16'(H2AK15Ub) of histone H2A regulating the DNA damage response at double-strand breaks (DSBs) (PubMed:27083998). USP51 is recruited to chromatin after DNA damage and regulates the dynamic assembly/disassembly of TP53BP1 and BRCA1. Exhibits also activity for 'Lys-27' or 'Lys-63'-linked di-ubiquitin (PubMed:27083998). Gene: USP51 
- 
                                            Molekulargewicht
- 80 kDa
- 
                                            Gen-ID
- 158880
- 
                                            UniProt
- Q70EK9
 Target
- 
                    
 
                                     
                                     
                                    