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TRIM14 Antikörper (C-Term)

TRIM14 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6265727
  • Target Alle TRIM14 Antikörper anzeigen
    TRIM14 (Tripartite Motif Containing 14 (TRIM14))
    Bindungsspezifität
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 18
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 17
    • 1
    Kaninchen
    Klonalität
    • 18
    Polyklonal
    Konjugat
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TRIM14 Antikörper ist unkonjugiert
    Applikation
    • 11
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    TRIM14 Antibody detects endogenous levels of total TRIM14.
    Homologie
    Pig,Bovine,Rabbit
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human TRIM14, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product TRIM14 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    TRIM14 (Tripartite Motif Containing 14 (TRIM14))
    Andere Bezeichnung
    TRIM14 (TRIM14 Produkte)
    Synonyme
    TRIM14 antikoerper, 5830400N10Rik antikoerper, pub antikoerper, tripartite motif containing 14 antikoerper, tripartite motif-containing 14 antikoerper, TRIM14 antikoerper, Trim14 antikoerper
    Hintergrund

    Description: Plays a role in the innate immune defense against viruses. Facilitates the type I IFN response by interacting with MAVS at the outer mitochondria membrane and thereby recruiting NF-kappa-B essential modulator IKBKG/NEMO to the MAVS signalosome, leading to the activation of both the IFN regulatory factor 3/IRF3 and NF-kappa-B pathways (PubMed:24379373). Positively regulates the CGAS-induced type I interferon signaling pathway by stabilizing CGAS and inhibiting its autophagic degradation (PubMed:27666593).

    Gene: TRIM14

    Molekulargewicht
    50 kDa
    Gen-ID
    9830
    UniProt
    Q14142
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