PAR1 Antikörper (N-Term)
Kurzübersicht für PAR1 Antikörper (N-Term) (ABIN6265563)
Target
Alle PAR1 (F2R) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Spezifität
- Thrombin Receptor Antibody detects endogenous levels of total Thrombin Receptor.
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Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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Immunogen
- A synthesized peptide derived from human Thrombin Receptor, corresponding to a region within N-terminal amino acids.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
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Haltbarkeit
- 12 months
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Inhibiting trophoblast PAR-1 overexpression suppresses sFlt-1-induced anti-angiogenesis and abnormal vascular remodeling: a possible therapeutic approach for preeclampsia." in: Molecular human reproduction, Vol. 24, Issue 3, pp. 158-169, (2018) (PubMed).
: "Doxycycline directly targets PAR1 to suppress tumor progression." in: Oncotarget, Vol. 8, Issue 10, pp. 16829-16842, (2017) (PubMed).
: "
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Inhibiting trophoblast PAR-1 overexpression suppresses sFlt-1-induced anti-angiogenesis and abnormal vascular remodeling: a possible therapeutic approach for preeclampsia." in: Molecular human reproduction, Vol. 24, Issue 3, pp. 158-169, (2018) (PubMed).
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- PAR1 (F2R) (Coagulation Factor II (thrombin) Receptor (F2R))
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Andere Bezeichnung
- F2R
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Hintergrund
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Description: High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in vascular development.
Gene: F2R
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Molekulargewicht
- 48kDa
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Gen-ID
- 2149
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UniProt
- P25116
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Pathways
- Nuclear Receptor Transcription Pathway, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus
Target
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